Amniotic Membrane market has been growing at a remarkable CAGR during the forecast period. Amnion is the innermost extraembryonic membrane that surrounds the fetus by forming an amniotic that contains amniotic fluid. In recent years, the amniotic membrane has advanced as a potential tool for the clinical application. It has been used as a medicine in order to stimulate the healing of skin and corneal diseases due to its bacteriostatic and pain reduction properties. Rising awareness about the properties of the amniotic membrane has led to increasing the transplant which in turn has increased the demand for tissue-based products. Also, the rise in the donation is observed as the awareness about the medical use of an amniotic membrane is growing thus fueling the global amniotic membrane market growth.
The presence of various growth factors in amniotic membrane including transforming growth factor, epidermal growth factor, keratinocyte growth factor, vascular endothelial growth factor, basic fibroblast growth factor, and nerve growth factor that promote wound healing process will increase the adoption of amniotic membrane across the globe. Amniotic membranes are now being used for a variety of indications including reconstruction of the conjunctive surface, pterygium excision, conceal ulcers or surgical wounds, regenerative medicines, and limbal stem cell deficiency. Therefore, factor such as an increase in the R&D investments in the stem cell and regenerative medicine is accelerating the global amniotic membrane market growth.
Moreover, the amniotic membrane has been used in the treatment of various forms of the ocular surface disease. The content of amniotic membranes such as pluripotent cells, anti-fibrotic and anti-inflammatory cytokines, highly organized collagen, immune modulator, and matrix proteins promote corneal healing in severely damaged eyes. Amniotic membrane extracts and amniotic membrane extract eye drops have been used in the clinical application including chemical burns and dry eyes. Several companies that produce products derived from amniotic membrane include Regenesol by Tissue Tech Inc., Genesis Amniotic Cytokine Extract (ACE) by Ocular Science Inc., AmnioGraft by Bio-Tissue, and Regener-Eyes.
None of the products is currently FDA regulated however, several of these products have obtained approval only for the distribution. There are many clinical trials going on to advance the use of amniotic membrane extracts for eye-related disorders. For instance, as per ClinicalTrials.gov, there are two clinical trials reported to be complete till now. The first one is “the improvement of limbal stem cell deficiency (LSCD) in unilateral stem cell damage by AMEED” and the second one is “utilization of amniotic membrane extract eye drop (AMEED) on human corneal healing”. Both the trials are from Labafi Nejad Eye Research Center situated in Tehran, Iran.
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Amniotic Membrane Market- Segmentation
By Application
- Ophthalmology
- Dermatology
- Otolaryngology
- Surgical Wound
- Orthopedic
- Others (Genitourinary Reconstruction)
By Type
- Dehydrated
- Cryopreserved
By End-User
- Ambulatory Surgical Centers
- Hospitals and Clinics
- Others (Research Institutes)
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Amniotic Membrane Market– Segment by Region
North America
- United States
- Canada
Europe
- Germany
- United Kingdom
- France
- Spain
- Italy
- Rest of Europe
Asia-Pacific
- China
- Japan
- India
- Rest of Asia-Pacific
Rest of the World
- Middle East & Africa
- Latin America
Company Profiles
- Alliqua BioMedical, Inc.
- Amnio Technology, LLC
- Applied Biologics, LLC
- AxoGen, Inc.
- Axolotl Biologix, Inc.
- BioStem Technologies, Inc.
- FzioMed, Inc.
- Human Regenerative Technologies, LLC
- Integra LifeSciences Corp.
- Katena Products, Inc.
- MiMedx Group, Inc.
- Orthofix Holdings, Inc.
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