The global acne therapeutics market is projected to grow significantly during the forecast period. The market is segmented on the basis of treatment and route of administration. Based on the treatment, the acne therapeutics market is further segmented into medications and other treatments. The medication includes retinoids, antibiotics, hormonal drugs, anti-inflammatory drugs, and others. Based on the route of administration, the market is segmented into oral, topical, and parenteral.
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The topical route of administration is primarily used for patients with non-inflammatory or mild inflammatory acne. It includes comedolytic agents such as tretinoin, benzoyl peroxide, antibiotics, and various anti-inflammatory drugs. The topical route of administration includes topical retinoids, topical antimicrobials, and topical antibiotics, among others. Topical retinoids include vitamin A derivatives, which are mainly used in patients with non-inflammatory acne, in combination with other topical and systemic drugs. Topical retinoids are also used as an alternative treatment when oral treatment is stopped. The retinoid used in the topical management of acne includes tretinoin, isotretinoin, adapalene, tazarotene, and retinaldehyde.
Topical antibiotics are very useful in the treatment of mild to moderate inflammatory acne vulgaris, however, no role in treating the comedonal phase of the disease. Erythromycin and clindamycin are the most commonly used topical antibiotics in acne treatment, both of which are available in different formulations. Antibiotics are not intended to be a monotherapy for acne. For instance, topical antibiotics should only be used in combination with benzoyl peroxide(BPO) to prevent the development of antibiotic-resistant bacteria.
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BPO is organic peroxide derived from a by-product of coal tar, which has become the most widely used topical acne medication in dermatology. BPO treatment alone improves inflammatory acne, and its mechanisms of action include antimicrobial, anti-inflammatory, and keratolytic effects and wound-healing activity. Fixed-dose combination gels of topical antibiotics with BPO are also available, as well as a combined gel formulation of clindamycin with tretinoin aids in treating acne.
Other topical agents including salicylic acid is a topical medication present in many over-the-counter products, which has comedolytic effects,however,it may be less effective than retinoids. Another topical agent, azelaic acid, has antibacterial, comedolytic and anti-inflammatory properties and is considered as a potential first-line monotherapy for female adult patients with acne, and a good choice for maintenancetherapy owing to its good tolerability and safety
Further, numerous players are operatingin the global acne therapeutics market that creates scope for market growth. Players such as Aclaris Therapeutics Inc., Allergan PlcEli Lilly and Co., F. Hoffmann-La Roche AG, LEO Pharma A/S, GlaxoSmithKline Plc, Mylan NV, Novartis AG, Pfizer Inc., Teva Pharmaceuticals Industries Ltd., Alma Lasers Ltd., Cynosure Inc., Suneva Medical Inc., and others are significantly contributing to the global acne therapeutics industry growth by adopting various growth strategies.
Global Acne Therapeutics Market – Segmentation
By Type
- Medication
- Other Treatment
By Route of Administration
- Oral
- Topical
- Parenteral
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