The global high affinity nerve growth factor receptor market is anticipated to grow at a significant CAGR during the forecast period (2021-2027). Nerve growth factor (NGF) is an insulin-like protein. It regulates the growth, development and maintenance of sympathetic and embryonic sensory neurons. The major factor driving the growth of the market is the increasing prevalence of atopic dermatitis across the globe.
According to the Allergy & Asthma Network, an estimated 18 million people have atopic dermatitis with 9.6 million children diagnosed with the condition in the US. Additionally, an estimated 3.2 million people have moderate to severe atopic dermatitis with more than 30% reported sleep disturbances due to the condition. Furthermore, it is more common in females than males. Moreover, AD poses a burden of $316 million per year globally. Apart from this, NGF mediates its effects in atopic dermatitis by binding to two classes of transmembrane receptors which include a high-affinity receptor and a low-affinity receptor. Hence, the increasing prevalence of atopic dermatitis is driving the demand for high affinity nerve growth factor receptors as it plays an important role in the treatment of pathogenesis of atopic dermatitis-like skin lesions which in turn is driving the growth of the market.
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Some major players in the market include Astellas Pharma Inc., Pfizer Inc., and Merck & Co Inc., among others. The market players are contributing significantly to the growth of the market by the adoption of various strategies including mergers & acquisitions, geographical expansion, partnerships and collaborations, and new product launches, to stay competitive in the market. For instance, in January 2020, Pfizer and Lilly filed for the approval of Tanezumab from the US FDA. It is a first-in-class NGF inhibitor at the lower 2.5mg dose used for the treatment of osteoarthritis pain.
Market Coverage
- The market number available for – 2020-2027
- Base year- 2020
- Forecast period- 2021-2027
Segment Covered-
- By Type
- By Application
Regions Covered-
- North America
- Europe
- Asia-Pacific
- Rest of the World
Competitive Landscape– Astellas Pharma Inc., Pfizer Inc., and Merck & Co Inc., among others.
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Global High Affinity Nerve Growth Factor Receptor Market Report by Segment
By Type
- ASP-7962
- AZD-7451
- BNN-27
- Cenegermin
- CRB-0089
- Others
By Application
- Atopic Dermatitis
- Cancer
- Others
Global High Affinity Nerve Growth Factor Receptor Market Report by Region
North America
- United States
- Canada
Europe
- UK
- Germany
- Spain
- France
- Italy
- Rest of Europe
Asia-Pacific
- India
- China
- Japan
- South Korea
- Rest of APAC
Rest of the World
- Latin America
- Middle East & Africa
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