The global DNA gyrase subunit B (EC 5.99.1.3) market is anticipated to grow at a significant CAGR during the forecast period (2021-2027). DNA gyrase is an essential bacterial enzyme that belongs to the topoisomerases class of enzymes that controls the topological transitions of DNA. Additionally, it catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. The major factor accelerating the growth of the market is the increasing prevalence of bacterial infections across the globe.
Moreover, based on application, the market is segmented into bacterial infections, clostridium diffclie infections, klebsiella pneumoniae infections, and others. Clostridium diffclie infections are anticipated to hold a major share in the market due to the rising incidence rate. According to the National Center for Biotechnology Information (NCBI), in 2017, there was an estimated 235,700 cases with an estimated incidence rate of 73.3 per 100,000 population in the US.
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Some major players in the market include Bristol-Myers Squibb Co., AstraZeneca Plc, and Merck & Co., Inc., among others. The market players are contributing significantly to the growth of the market by the adoption of various strategies including mergers & acquisitions, geographical expansion, partnerships and collaborations, and new product launches, to stay competitive in the market. For instance, in October 2019, GlaxoSmithKline Plc announced the beginning of patient dosing in a phase III clinical programme investigating gepotidacin. Gepotidacin is a new chemical class of antibiotics called triazaacenaphthylene bacterial topoisomerase inhibitors used for the treatment of patients with uncomplicated urinary tract infection and urogenital gonorrhoea (GC). The drug works by interacting with two key bacterial enzymes, DNA gyrase and topoisomerase IV
Market Coverage
- The market number available for – 2020-2027
- Base year- 2020
- Forecast period- 2021-2027
Segment Covered-
- By Type
- By Application
Regions Covered-
- North America
- Europe
- Asia-Pacific
- Rest of the World
Competitive Landscape– Bristol-Myers Squibb Co., AstraZeneca Plc, and Merck & Co., Inc., among others.
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Global DNA Gyrase Subunit B (EC 5.99.1.3) Market Report by Segment
By Type
- GYR-12
- DS-2969
- VXC-100
- VT-12008911
- Others
By Application
- Bacterial Infections
- Clostridium Diffclie Infections
- Klebsiella Pneumoniae Infections
- Others
Global DNA Gyrase Subunit B (EC 5.99.1.3) Market Report by Region
North America
- United States
- Canada
Europe
- UK
- Germany
- Spain
- France
- Italy
- Rest of Europe
Asia-Pacific
- India
- China
- Japan
- South Korea
- Rest of APAC
Rest of the World
- Latin America
- Middle East & Africa
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