Global CRISPR and Cas genes market is anticipated to grow at a CAGR of 13.5% during the forecast period (2023-2030). The technological advancements in CRISPR & Cas gene systems have contemporarily revolutionized the area of cancer research and therapeutics. As the prevalence of genetic diseases and complex medical conditions continues to rise, there is an increasing demand for innovative treatments that can target the root cause of these ailments. CRISPR-Cas systems are effective and effortlessly programmable nucleic acid-targeting tools. The use of CRISPR-Cas systems in bacterial activities, increase in research and development expenditure by governments in the fields of genome editing, rise in the presence of genetic diseases, and the use of CRISPR technology to advance crop production have been the key drivers of the CRISPR and Cas genes market globally.
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Closed-end dsDNA enables researchers to perform gene knock-in with higher efficiency and lower toxicity than traditional PCR methods and is ideally suited for large-scale screening and scale-up in cell and gene therapy. In November 2021, GenScript Inc. launched the GenWand™ Double-Stranded DNA (dsDNA) Service for the manufacture of CRISPR knock-in homology-directed repair (HDR) templates in T-cell engineering. Non-viral vector delivery has clear advantages – including safety – in CRISPR/Cas applications for gene and cell therapy.
Antibody-targeted adeno-associated virus (AAV) vectors and delivery systems and proprietary Nme2 CRISPR/Cas9 (Nme2Cas9) systems adapted for viral vector delivery and designed to precisely modify a target gene. In October 2023, Regeneron Pharmaceuticals, Inc. and Intellia Therapeutics, Inc. collaborated to develop additional in vivo CRISPR-based gene editing therapies focused on neurological and muscular diseases.
Various companies provide scientific objectives to decode all rejuvenation programs present in human cells, and to build an atlas of disease and rejuvenation targets for clinical translation. For instance, in August 2023, clock.bio launched to decode rejuvenation biology across the human genome. The company has developed an aging model that force-ages human induced pluripotent stem cells (hiPSCs) and triggers their self-rejuvenation mechanism. Unbiased CRISPR screens on large samples of these cells allow for the identification of gene candidates that are causally relevant for cell rejuvenation.
Market Coverage
- The market number available for – 2022-2030
- Base year- 2022
- Forecast period- 2023-2030
- Segment Covered-
o By Product Type
o By Service Type
o By Application
o By End Users
- Regions Covered-
o North America
o Europe
o Asia-Pacific
o Rest of the World
- Competitive Landscape- Danaher Corp., GenScript Biotech, Merck KGaA, Thermo Fisher Scientific, Inc., Bio-Rad Laboratories, Inc., GE Healthcare, Qiagen NV, and others.
Key questions addressed by the report
- What is the market growth rate?
- Which segment and region dominate the market in the base year?
- Which segment and region will project the fastest growth in the market?
- Who is the leader in the market?
- How are players addressing challenges to sustain growth?
- Where is the investment opportunity?
Global CRISPR and Cas Genes Market Report Segment
By Product Type
- Vector-based Cas
- DNA-free Cas
By Service Type
- Cell Line Engineering
- gRNA design
- Microbial Gene Editing
- DNA Synthesis
By Application
- Genome Engineering
- Disease Models
- Functional Genomics
- Other (Biomedical)
By End Users
- Biotechnology Companies & Pharmaceutical
- Academic and Government Research Institute
- CROs
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Company Profiles
- ACROBiosystems, Inc.
- Agilent Technologies, Inc.
- Bio-Rad Laboratories, Inc.
- Caribou Biosciences, Inc.
- Cell Biolabs, Inc.
- Cellecta, Inc.
- Creative Biogene.
- CRISPR Therapeutics AG
- Editas Medicine, Inc.
- GE Healthcare
- Horizon Discovery Group plc
- Illumina, Inc.
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